ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.

Hu SB, Heraud-Farlow J, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR, Li JB.

Mol Cell. 2023 Nov 2;83(21):3869-3884.e7. doi: 10.1016/j.molcel.2023.09.018. Epub 2023 Oct 4. PMID: 37797622

Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo.

Mendez Ruiz S, Chalk AM, Goradia A, Heraud-Farlow J, Walkley CR.

NAR Cancer. 2023 Jun 1;5(2):zcad023. doi: 10.1093/narcan/zcad023. eCollection 2023 Jun. PMID: 37275274

The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.

Liang Z, Chalk AM, Taylor S, Goradia A, Heraud-Farlow JE, Walkley CR.

EMBO Rep. 2023 May 4;24(5):e55835. doi: 10.15252/embr.202255835. Epub 2023 Mar 28. PMID: 36975179

The absence of core piRNA biogenesis factors does not impact efficient transposon silencing in Drosophila

Chary S, Hayashi R.

PLoS Biol 21(6): e3002099. https://doi.org/10.1371/journal.pbio.3002099

Nuclear export of circular RNA

Linh H. Ngo, Andrew G. Bert, B. Kate Dredge, Tobias Williams, Vincent Murphy, Wanqiu Li, William B. Hamilton, Kirstyn T. Carey, John Toubia, Katherine A. Pillman, Dawei Liu, Jessica Desogus, Jeffrey A. Chao, Andrew J. Deans, Gregory J. Goodall & Vihandha O. Wickramasinghe

A structural analysis of the nsp9 protein from the coronavirus MERS CoV reveals a conserved RNA binding interface

Gayathri Mani, Serene El-Kamand, Bing Wang, David L Baker, Sandro F Ataide, Irina Artsimovitch, Liza Cubeddu, Roland Gamsjaeger

PMID: 37929701. PMCID: PMC10872591 (available on 2024-09-01), DOI: 10.1002/prot.26630

Artificial intelligence and machine learning in RNA biology

Kathi Zarnack, Eduardo Eyras

A better way to create nanoparticles for in vivo treatments

Peter Davis

(2023) Identification of cell barcodes from long-read single-cell RNA-seq with BLAZE

You Y, Prawer YDJ, De Paoli-Iseppi R, Hunt CPJ, Parish CL, Shim H and Clark MB

Genome Biol. 24: 66

NONO enhances mRNA processing of super‐enhancer‐associated GATA2 and HAND2 genes in neuroblastoma

S Zhang, JAL Cooper, YS Chong, A Naveed, C Mayoh, N Jayatilleke

EMBO reports 24 (2), e54977

mRNA vaccine against malaria tailored for liver-resident memory T cells

Mitch Ganley, Lauren E. Holz, Jordan J. Minnell, Maria N. de Menezes, Olivia K. Burn, Kean Chan Yew Poa, Sarah L. Draper, Kieran English, Susanna T. S. Chan, Regan J. Anderson, Benjamin J. Compton, Andrew J. Marshall, Anton Cozijnsen, Yu Cheng Chua, Zhengyu Ge, Kathryn J. Farrand, John C. Mamum, Calvin Xu, Ian A. Cockburn, Katsuyuki Yui, Patrick Bertolino, Stephanie Gras, Jérôme Le Nours, Jamie Rossjohn, Daniel Fernandez-Ruiz, Geoffrey I. McFadden, David F. Ackerley, Gavin F. Painter, Ian F. Hermans & William R. Heath

Fear extinction is regulated by the activity of long noncoding RNAs at the synapse

Liau WS, Zhao Q, Bademosi A, Gormal RS, Gong H, Marshall PR, Periyakaruppiah A, Madugalle SU, Zajaczkowski EL, Leighton LJ, Ren H, Musgrove M, Davies J, Rauch S, He C, Dickinson BC, Li X, Wei W, Meunier FA, Fernández-Moya SM, Kiebler MA, Srinivasan B, Banerjee S, Clark M, Spitale RC, Bredy TW

Nat Commun. 2023 Nov 22;14(1):7616. doi: 10.1038/s41467-023-43535

Synapse-Enriched m6A-Modified Malat1 Interacts with the Novel m6A Reader, DPYSL2, and Is Required for Fear-Extinction Memory.

Madugalle SU, Liau WS, Zhao Q, Li X, Gong H, Marshall PR, Periyakaruppiah A, Zajaczkowski EL, Leighton LJ, Ren H, Musgrove MRB, Davies JWA, Kim G, Rauch S, He C, Dickinson BC, Fulopova B, Fletcher LN, Williams SR, Spitale RC, Bredy TW

J Neurosci. 2023 Oct 25;43(43):7084-7100. doi: 10.1523/JNEUROSCI.0943-23.2023

RNA-binding proteins in cardiovascular biology and disease: the beat goes on

Völkers, M., Preiss, T. & Hentze, M.W.

Nat Rev Cardiol (2024).

PERSPECTIVE: The je ne sais quoi of 5-methylcytosine in messenger RNA 

Marco Guarnacci and Thomas Preiss

RNA May 2024 30: 560-569; Published in Advance March 26, 2024, doi:10.1261/rna.079982.124

Fundamental Neurochemistry Review: At the intersection between the brain and the immune system: Non-coding RNAs spanning learning, memory and adaptive immunity

Mason R. B. Musgrove, Marina Mikhaylova, Timothy W. Bredy

Fear extinction is regulated by long noncoding RNA activity at the synapse.

Liau WS., Zhao Q., Bademosi A., Gormal R., Gong H., Marshall P.R., Periyakaruppiah A., Madugalle S.U., Zajackowski E.L., Leighton L.J., Ren H., Musgrove M., Davies J., Rauch S., He C., Dickinson B.C., Li X., Wei W., Meunier F.A., Fernandez Moya SM., Kiebler M.A., Srinivasan B., Banerjee S., Clark M., Spitale R.C., Bredy T.W.

Nature Communication, 14(1): 7616, 2023

Synapse-enriched m6A-modified Malat1 interacts with the novel m6A reader, DPYSL2, and is required for fear-extinction memory.

Madugalle SU.#, Liau WS.#, Zhao Q., Li X., Gong H., Marshall P.R., Periyakaruppiah A.,., Zajackowski E.L., Leighton LJ., Ren H.B., Musgrove M., Davies J., Kim G.M., Rauch S., He C., Dickinson B.C., Fletcher L., Fulopova B., Williams S.R., Spitale R.C., Bredy T.W.

Journal of Neuroscience, 43 (43) 7084-7100, 2023: # Equal contribution

RIL-seq reveals extensive involvement of small RNAs in virulence and capsule regulation in hypervirulent Klebsiella pneumoniae

Kwok Jian Goh, Yael Altuvia, Liron Argaman, Yair Raz, Amir Bar, Trevor Lithgow, Hanah Margalit, Yunn-Hwen Gan

Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress

Attila Horvath, Yoshika Janapala, Katrina Woodward, Shafi Mahmud,  Alice Cleynen, Elizabeth E Gardiner, Ross D Hannan, Eduardo Eyras, Thomas Preiss, Nikolay E Shirokikh

Dynamics of mRNA fate during light stress and recovery: from transcription to stability and translation

Aaron B. Smith, Diep R. Ganguly, Marten Moore, Andrew F. Bowerman, Yoshika Janapala, Nikolay E. Shirokikh, Barry J. Pogson, Peter A. Crisp

Targeting the ribosome to treat multiple myeloma

Maclachlan KH, Gitareja K, Kang J, Cuddihy A, Cao Y, Hein N, Cullinane C, Ang CS, Brajanovski N, Pearson RB, Khot A, Sanij E, Hannan RD, Poortinga G, Harrison SJ

Mol Ther Oncol. 2024 Feb 7;32(1):200771. doi: 10.1016/j.omton.2024.200771. PMID: 38596309; PMCID: PMC10905045.

ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation

Hu S*, Heraud-Farlow JE*, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR†, Li JB†

Mol Cell 83(21):3869-3884